Stiff-Person syndrome and generalized anxiety disorder

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Stiff-person syndrome and generalized anxiety disorder.

Master Degree Student, Laboratory of Panic & Respiration, Institute of Psychiatry, Federal University of Rio de Janeiro, INCT Translational Medicine, Rio de Janeiro RJ, Brazil; Assistant Professor, Neurology Service, State of Rio de Janeiro University, Rio de Janeiro RJ, Brazil; Assistant Professor, Federal University of State of Rio de Janeiro, Rio de Janeiro RJ, Brazil; Associate Professor. L...

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Stiff Person Syndrome.

Stiff-person syndrome or Moersch-Woltmann is a very rare and disabling neurologic disorder characterized by muscle rigidity and episodic spasms involving axial and limb musculature. It is an autoimmune disorder resulting in a malfunction of aminobutyric acid mediated inhibitory networks in the central nervous system. We describe a patient of stiff person syndrome.

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Stiff person syndrome.

Recognizing stiff person syndrome is clinically important. It is uncommon, characterized by body stiffness associated with painful muscle spasms, and varies in location and severity. It is subdivided into stiff trunk versus stiff limb presentation, and as a progressive encephalomyelitis. Stiff person-type syndrome also reflects a paraneoplastic picture. Most patients demonstrate exaggerated lum...

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Stiff-person syndrome.

The stiff-person syndrome is a disorder of persistent, painful muscle contractions predominately affecting the axial musculature. We describe a patient with this disorder and review its pathophysiology. Molecular biologic and immunologic techniques have recently added to the understanding of the mechanism of this disorder. Association with diseases such as diabetes, vitiligo and hypothyroidism ...

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['Stiff-person'-syndrome].

In two patients, a man aged 54 years and a woman aged 49 years, stiff-person syndrome was diagnosed. This is a rare disorder of the central nervous system, with signs of an autoimmune pathogenesis. Patients present with pain and stiffness of the lower back, a complaint that is regularly seen in general practice. Moreover, the disease causes hypertonia and very painful cramps of the lower back a...

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ژورنال

عنوان ژورنال: Arquivos de Neuro-Psiquiatria

سال: 2010

ISSN: 0004-282X

DOI: 10.1590/s0004-282x2010000400036